睡眠呼吸暂停风险,主观认知衰退和认知表现:波士顿拉丁裔老龄化研究的发现
Celina McDowell1,2,3, Averi Giudicessi1,2, Jairo Enrique Martinez1,2
1Department of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.
Dementia and geriatric cognitive disorders
|November 25, 2024
概括
自我报告的阻塞性睡眠呼吸暂停 (OSA) 风险没有预测老拉丁裔的认知衰退或主观认知衰退. 需要进一步的研究来确定这一群体的认知能力下降风险.
科学领域:
- 神经学 神经学
- 老年学是指老年学的学科.
- 睡眠医学 睡眠医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 与认知能力下降和痴呆症有关,但这种关系在不同的人群中未得到充分研究.
- 研究OSA对老年拉丁裔认知健康的影响对于了解健康差异至关重要.
研究的目的:
- 检查老拉丁裔中自我报告的OSA风险与主观认知衰退 (SCD) 之间的关联.
- 评估这个社区居民群体中OSA风险和客观认知表现之间的关系.
主要方法:
- 来自波士顿拉丁裔老龄化研究 (BLAST) 的112名老拉丁裔成年人完成了认知评估 (PACC5,MMSE) 和关于OSA风险 (柏林问卷) 和SCD (CFI) 的问卷.
- 使用等级回归和t测试来分析OSA风险,SCD和认知表现之间的关联,控制人口统计.
主要成果:
- 在OSA风险和主观认知衰退 (SCD) 之间没有发现显著的关联.
- 阻塞性睡眠呼吸暂停 (OSA) 风险没有预测临床前阿尔茨海默氏症认知复合-5 (PACC5) 或全球认知 (MMSE) 的表现.
- 低和高OSA风险的参与者之间没有观察到认知差异.
结论:
- 初步发现表明,自我报告的OSA风险可能不是老拉丁裔认知能力下降风险的可靠指标.
- 目前的OSA查问卷可能需要与其他评估进行整合,以有效地识别这一人口中的认知衰退.
- 更大的样本大小和正在进行的研究是必要的,以进一步阐明OSA和认知健康之间的复杂关系在不同的老龄化人口中.
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