使用智能手机数据频繁测量无形皮肤炎的严重程度和了解触发因素:一个分散的12周观察性研究
Zarqa Ali1, Johan Anker Chrom Allerup1, Anders Daniel Andersen2
1Department of Dermato-Venereology and Wound Healing Centre, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark.
概括
智能手机照片有效监测了阿托皮性皮肤炎 (AD) 严重程度,与患者报告的结果和温度和CO等环境因素相关联. 这种远程方法为更好的AD管理提供了持续的疾病跟踪.
科学领域:
- 皮肤病学 皮肤病学
- 数字健康数字健康
- 环境健康 环境健康
背景情况:
- 传统的亚托皮性皮炎 (AD) 评估是偶发性的,缺少疾病波动.
- 持续监测对于了解AD爆发和缓解至关重要.
- 智能手机技术为频繁的AD严重程度评估提供了一种新的方法.
研究的目的:
- 通过智能手机摄影来评估AD的严重程度.
- 为了将频繁的摄影AD评估与患者报告的结果 (POEM) 相关联起来.
- 调查AD波动,环境数据 (温度,CO) 和精神病相关疾病之间的关联.
主要方法:
- 一项为期12周的分散观察性研究,涉及在线招募的成年AD患者.
- 参与者使用智能手机应用程序进行每周的摄影评估和POEM完成.
- 从照片中使用湿疹区域和严重性指数 (EASI) 和Atopic皮炎评分 (SCORAD) 来量化AD严重程度.
- 环境数据 (环境温度,CO) 根据参与者的位置获取.
主要成果:
- 摄影SCORAD和EASI与患者报告的POEM分数有显著的相关性.
- 阿尔茨海默病的波动与患精神疾病,特别是焦虑和抑郁症的风险更高有关.
- 温度下降与AD严重程度的增加相关 (POEM,EASI).
- 升高的一氧化碳 (CO) 水平与更高的SCORAD分数有关.
结论:
- 基于智能手机的远程摄影评估对于监测AD严重程度是可行的.
- 这种方法可以持续跟踪疾病活动和患者报告的结果.
- 环境因素和精神病相关疾病与阿尔茨海默病的波动有显著的关联.
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