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改变的线粒体展开蛋白质反应和蛋白质质量控制促进了唐氏综合征大脑中的氧化应激

Simona Lanzillotta1, Daniel Esteve2, Chiara Lanzillotta1

  • 1Department of Biochemical Sciences "A. Rossi-Fanelli", Sapienza University of Rome, Rome, Italy.

Free radical biology & medicine
|November 25, 2024
PubMed
概括

线粒体功能障碍和氧化应激是唐氏综合征 (DS) 大脑发育的早期特征. 准线粒体蛋白质质量控制途径可能为DS神经发育缺陷提供治疗策略.

关键词:
大脑发育 大脑发育唐氏综合征是什么意思 唐氏综合征线粒体代谢的代谢过程氧化应激是一种氧化应激.在UPRmt中使用UPRmt.

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