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老年人中的炎症性肠病负担,1990-2019:基于全球疾病负担研究2019年的系统分析
Liji Chen1, Shaoyu Cheng1, Beiping Zhang2
1The Second Clinical Medical College of Guangzhou University of Traditional Chinese Medicine, Guangzhou, China.
Autoimmunity reviews
|November 25, 2024
概括
在老年人中,炎症性肠病 (IBD) 的全球负担显著增加,病例和死亡人数增加. 然而,IBD发病率,流行率和死亡率的年龄标准化率在全球范围内有所下降.
科学领域:
- 老年医学 老年医学
- 胃肠病学 胃肠病学
- 公共卫生流行病学 流行病学
背景情况:
- 在老年人群中,炎症性肠病 (IBD) 的患病率大幅上升.
- 了解老年人IBD的全球健康负担对于未来的医疗保健规划至关重要.
研究的目的:
- 综合评估1990年至2019年年龄在老年人群中的IBD全球负担.
- 分析不同地区和人口统计数据中老年人IBD负担的趋势和差异.
主要方法:
- 2019年利用的全球疾病负担研究 (GBD) 关于在2010-2019年期间患有IBD的60-89岁成年人患病率,发病率,DALY和死亡率的数据.
- 分析了使用1990-2019年年龄标准化利率 (ASR) 估计年均百分比变化 (EAPC) 的趋势.
- 根据地区,国家,社会人口指数 (SDI),年龄组和性别进行子组分析.
主要成果:
- 在老年人中,IBD流行病例,事件病例,DALY和死亡病例的总数从1990年至2019年显著增加.
- 在全球范围内,IBD发病率,流行率,DALY和死亡率的年龄标准化率呈现下降趋势.
- 在美洲,欧洲地区和高SDI国家观察到高IBD负担;在中等SDI国家流行/发病率增长最快.
- 流行率,发病率和DALY的最高年龄标准化率在60-64岁年龄组中,而死亡率在80-89岁年龄组中最高. 没有发现明显的性别差异.
结论:
- 由于病例数量和死亡率的增加,老年人的IBD代表着日益增长的全球公共卫生挑战.
- 在IBD负担中存在显著的区域,国家和特定年龄的变化.
- 有针对性的公共卫生战略对于减轻老年人IBD疾病负担至关重要.
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