感染性内心炎的发病率在患有多变性心肌病的患者中
Somyata Somendra1, Saurabh Mehrotra1, Parag Barwad1
1Department of Cardiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Indian heart journal
|November 25, 2024
概括
传染性内心炎 (IE) 很少发生在高增多性心肌病 (HCM) 患者中,每1000个患者年发生0.92例. 然而,在HCM中,IE显著增加了发病率和死亡率风险.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 临床研究 临床研究
背景情况:
- 有限的数据存在于感染性内心炎 (IE) 在患有多变性心肌病 (HCM) 的患者的发病率.
- 这项研究旨在确定一个明确的HCM患者队列中的IE发病率.
研究的目的:
- 评估在被诊断患有多变性心肌病 (HCM) 的患者中感染性内心炎 (IE) 的发生率.
主要方法:
- 从2003年5月到2023年6月对529名HCM患者的回顾性队列分析.
- 包括标准要求诊断HCM和至少一个后续访问.
- 在队列进入后的IE诊断是主要结果.
主要成果:
- 在529名HCM患者中,有3人 (0.57%) 在3244.6年的总随访时间内发展出IE.
- 在HCM患者中,IE的总发病率为每1000个患者年0.92.
- IE发生在阻塞性 (1.39/1000患者年) 和非阻塞性 (0.55/1000患者年) HCM中,其中关节涉导致严重并发症.
结论:
- 传染性内心炎是超性心肌病患者的罕见并发症.
- 尽管很罕见,但HCM中的IE与显著的发病率和死亡率有关.
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