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Updated: Jun 6, 2025

Generation of Alginate Microspheres for Biomedical Applications
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设计,合成和生物评估酸盐寡糖衍生物的设计,合成和生物评估

Wenkang Guo1, Manchun Chen2, Changjie Zou3

  • 1School of Pharmacy, Anhui University of Chinese Medicine, Hefei 230000, China; Yangtze Delta Drug Advanced Research Institute and Yangtze Delta Pharmaceutical College, Nantong 226133, China; Haitang (Jiangsu) Biotechnology Co, Ltd, Nantong 226133, China.

Bioorganic & medicinal chemistry letters
|November 25, 2024
PubMed
概括

新型酸寡糖衍生物显示出作为急性损伤 (AKI) 的潜在治疗方法的前景. 化合物2a和2b在初步研究中表现出显著的治疗活性,与现有治疗方法相比.

关键词:
急性损伤是什么?急性损伤是什么?酸类寡糖化物.酸的寡糖化合物衍生物

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Oligosaccharide Assembly01:24

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Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
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