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Updated: May 13, 2026

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来自各种免疫图书馆的抗体数据分析

Ahmed S Fahad1,2, Matías F Gutiérrez-Gonzalez1,2, Bharat Madan1

  • 1The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Cambridge, Massachusetts 02139, USA.

Cold Spring Harbor protocols
|November 25, 2024
PubMed
概括

本研究提出了一项分析功能查中的抗体基因序列数据的协议. 它可以使用丰富比率来量化和映射抗体库,以改善抗体发现.

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Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...