复发性鼻多重症的危险因素和并发症
Hossein Esmaeilzadeh1, Babak Shahhosseini2, Mohammad Amin Gholami3
1Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran AND Department of Allergy and Clinical Immunology, Namazi Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. esmailzadeh_ho@yahoo.com.
确定了复发性慢性鼻炎与鼻息肉 (CRSwNP) 的预测因素. 较高的IgE水平和更严重的喘与复发有关,而在非复发病例中,阳性过敏测试更常见.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏和免疫学 过敏和免疫学
- 呼吸系统医学 呼吸系统医学
背景情况:
- 经过手术后,常常会出现复发性带鼻息肉的慢性鼻鼻炎 (CRSwNP).
- 在CRSwNP中治疗耐药性和复发的预测因素在很大程度上是未知的.
研究的目的:
- 识别和评估与耐治疗和复发性CRSwNP相关的风险因素.
- 分析CRSwNP患者的人口结构和亚托皮因素.
主要方法:
- 对191名CRSwNP患者的横截面研究.
- 评估人口统计数据,IgE水平,皮肤刺伤测试 (SPT) 气体过敏原和喘患病率.
- 通过口服阿司匹林挑战诊断阿司匹林恶化呼吸道疾病 (AERD).
主要成果:
- 与非复发病例相比,复发性CRSwNP患者的喘患病率和严重程度显著增加.
- 在复发性CRSwNP和AERD患者中观察到IgE水平升高.
- 对过敏原的SPT阳性结果在非复发性CRSwNP组中更为频繁.
结论:
- 较高的IgE水平和喘严重程度的增加与复发性CRSwNP有关.
- 阿司匹林加剧的呼吸道疾病与高IgE和更严重的CRSwNP喘有关.
- 过敏原敏感化模式在复发性和非复发性CRSwNP之间有所不同.
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