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Updated: Jun 6, 2025

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes
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Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

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将产前和产后婴儿暴露与生理学基础的药动力学建模相结合,以预测母婴在母乳养期间累计暴露于Levétiracetam的情况

Santosh V Suryavanshi1, Shirley Wang1, Dagmar M Hajducek1

  • 1School of Pharmacy, University of Waterloo, Kitchener, ON, Canada.

Clinical pharmacokinetics
|November 25, 2024
PubMed
概括

这项研究将婴儿的产前和产后 levetiracetam 暴露整合起来,表明联合暴露可能接近新生儿的治疗水平. 开发的模型有助于识别婴儿在母乳养期间面临潜在毒性风险.

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