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Co-Translational Insertion of Membrane Proteins into Preformed Nanodiscs
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膜蛋白序列直接翻译后插入的特点

Ilya A Kalinin1, Hadas Peled-Zehavi1, Alon B D Barshap1

  • 1Department of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, Israel.

Nature communications
|November 25, 2024
PubMed
概括

许多膜蛋白 (MPs) 使用后翻译途径进行C端螺旋体插入,由特定的C尾序列和YidC插入酶指导. 这确保了适当的蛋白质折叠,并预防疾病.

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