在诊断出鼻炎后,视网膜静脉封闭疾病的后续风险:全国性基于人口的研究
Tsan-Yu Tsai1, Jing-Yang Huang2,3, Shih-Chun Chao1,4,5
1Department of Ophthalmology, Show Chwan Memorial Hospital, Changhua, Taiwan.
Scientific reports
|November 25, 2024
概括
鼻炎患者面临患视网膜静脉封闭 (RVO) 的更高风险,这是视力丧失的常见原因. 这项研究发现,鼻炎与RVO发病率增加之间存在显著的关联.
科学领域:
- 眼科医生 眼科 眼科
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 流行病学 流行病学
背景情况:
- 视网膜静脉封闭 (RVO) 是一种普遍的血管疾病,导致视力受损.
- 有限的研究存在于鼻炎和发展RVO的风险之间的潜在联系.
研究的目的:
- 为了调查鼻炎病史与随后的RVO风险之间的关联.
- 测量与没有鼻炎的人相比,鼻炎患者的RVO风险.
主要方法:
- 一项回顾性,基于人口的队列研究,利用台湾国家健康保险研究数据库 (NHIRD).
- 确定了131532名被诊断患有鼻炎的患者,并根据年龄和性别与263064名对照进行了匹配.
- 考克斯比例危险回归分析用于确定调整的危险比率 (aHR) 和95%置信区间 (CI).
主要成果:
- 鼻炎队列对RVO的原始危险比率 (cHR) 显著更高,为1.35 (95% CI: 1.20-1.52).
- 在多变量调整后,调整后的危险率 (aHR) 仍然高,为1.28 (95% CI:1.13-1.44).
- 在鼻炎队列中观察到14年累计发病率的RVO,中央RVO和分支RVO的统计显著增加.
结论:
- 鼻炎被确定为与发展RVO的可能性增加相关的危险因素.
- 这些发现表明,鼻炎的炎症过程与视网膜血管事件的病变发生之间存在潜在的联系.
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