英国儿童喘的流行病学
Imène Gouia1, Florence Joulain1, Yi Zhang2
1Health Economics and Value Assessment, Sanofi, Gentilly, France.
Journal of asthma and allergy
|November 26, 2024
概括
儿童喘影响6.5%的英国儿童,较高的严重程度与更严重的症状和更多的并发症有关. 这凸显了英国儿童喘的重大负担.
科学领域:
- 儿科肺病学 儿科肺病学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 儿童喘患病率及其相关负担在全球范围内不断增加.
- 英国近期关于儿童喘的流行病学数据有限.
- 喘是英国儿童中最常见的慢性疾病.
研究的目的:
- 为了确定英国儿科喘的患病率.
- 评估患有喘儿童的疾病负担,包括症状,并发症和治疗方法.
- 分析喘严重程度与患者结果之间的关系.
主要方法:
- 来自临床实践研究数据链接 (2017) 的19,330名儿童 (6-11岁) 的回顾性纵向数据库分析.
- 根据使用全球喘倡议 (GINA) 2017年指南的严重程度评估喘患病率.
- 在喘患者和匹配的非喘对照人群之间比较症状,并发症和治疗方法;对症状进行后勤回归.
主要成果:
- 英国儿科喘患病率估计为6.5% (轻度:74.2%,中度:15.0%,重度:10.8%).
- 较高的喘严重程度与日间和夜间症状增加相关,并影响日常活动.
- 与对照组相比,喘患者表现出更高的并发病率,尤其是亚托皮性皮肤炎和过敏性鼻炎.
结论:
- 喘仍然是英国儿童患病的重要原因.
- 喘严重程度的增加与更大的症状负担有关.
- 患有喘的儿童比不患喘的同龄人更容易患上并发症.
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