血动脉生成指数与外围动脉疾病之间的关联
Huiqi Hong1, Lei Wu1, Shaofang Chen1
1Department of Pharmacy, Shunde Hospital of Southern Medical University, Foshan, China.
VASA. Zeitschrift fur Gefasskrankheiten
|November 26, 2024
概括
血的动脉原体指数 (AIP) 与较高的周围动脉疾病 (PAD) 风险有关. AIP的增加与美国成年人患PAD的发病率更高有关.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
- 流行病学 流行病学
背景情况:
- 甲基性脂质失调是周围动脉疾病 (PAD) 的已知前体.
- 有限的研究存在于美国社区人群中Atherogenic Plasma Index (AIP) 和PAD之间的关联.
研究的目的:
- 使用基于美国人口的数据集,研究AIP和PAD之间的关系.
- 为了确定AIP是否是PAD发病率的独立预测因素.
主要方法:
- 从国家健康和营养检查调查 (1999-2004) 中分析了3,517名参与者.
- AIP计算为log10 (三糖化物/高密度脂蛋白胆固醇).
- 进行了后勤回归模型,分层和相互作用分析.
主要成果:
- 较高的AIP三位数与增加的PAD患病率相关.
- 在多变量调整 (OR=1.30) 后,观察到AIP和PAD之间的积极关联.
- 与最低的 (OR=1.50) 相比,最高的AIP三位数显示PAD风险增加了50%.
结论:
- 在美国成年人中,AIP和PAD发病率之间存在显著的积极关联.
- 一个单位的AIP增加与30%的PAD风险增加有关.
- 这种关联在各种人口子组中保持一致.
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