心理测量验证和确定 Bronchiectasis 的成年人的 Bronchiectasis 健康问卷的最小临床重要差异
Jin-Fu Xu1,2, Surinder S Birring3,4, Yuan-Yuan Li5
1Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, Institute of Respiratory Medicine, School of Medicine, Tongji University, Shanghai, China.
Annals of the American Thoracic Society
|November 26, 2024
概括
支气管病症健康问卷 (BHQ) 是测量支气管病患者生活质量的验证工具. BHQ分数的3分变化表明临床上重要的差异,有助于治疗评估.
科学领域:
- 肺部病理学 肺部病理学
- 临床研究 临床研究
- 健康结果的健康结果.
背景情况:
- 支气管切开症健康问卷 (BHQ) 是评估支气管切开症患者与健康有关的生活质量的关键工具.
- 验证心理测量属性和确定临床重要差异最小值 (MCID) 对于其在临床实践中的可靠使用至关重要.
研究的目的:
- 为了研究BHQ的简化普通话版本的心理测量特性.
- 确定BHQ的MCID作为评估支气管切开症治疗的可靠临床终点.
主要方法:
- 纵向随机对照试验 (n=357) 和支气管切除症患者的横截面观察队列 (n=436) 的分析.
- 心理测量评估包括趋同有效性,已知组有效性,内部一致性,测试重试可靠性和响应性.
- 使用基于和基于分布的方法计算MCID.
主要成果:
- 中国普通话BHQ与生命质量-支气管切开症呼吸道症状量表 (r=0.698和0.567,P<0.0001) 显示出强烈的相关性.
- 根据支气管病重症指数,BHQ得分显示出显著差异,与肺功能和恶化频率相关.
- 观察到优异的内部一致性 (克朗巴赫的α=0.893) 和测试复试可靠性 (ICC=0.853).
- 对BHQ的MCID始终被确定为3分.
结论:
- 简体中文BHQ是用于评估支气管切除症患者的生活质量的心理测量仪器.
- BHQ分数的3个点变化代表了MCID,这意味着患者在临床上有意义的改善.
- BHQ作为一个有价值的工具,用于评估治疗干预措施和患者为中心的结果在支气管切除症管理.
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