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Updated: Jun 6, 2025

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饮食增强的LRG1表达促进胰腺β细胞中的胰岛素过分分泌和ER压力

Desirae D Morales1, Jiyoon Ryu1, Cong Wei1

  • 1Department of Cell Systems & Anatomy, The University of Texas Health San Antonio, San Antonio, TX, USA.

Diabetologia
|November 26, 2024
PubMed
概括

血清中的富含白的α-2-糖蛋白1 (LRG1) 在饮食诱导的肥胖症中促进高胰岛素血症和β细胞功能障碍. 中和LRG1活动为2型糖尿病提供了潜在的治疗策略.

关键词:
艾迪波基因 (Adipokine) 是一种可怕的药物.贝塔细胞衰竭的原因贝塔细胞 贝塔细胞 贝塔细胞在Ca2+信号传输中.压力ERER压力ERER压力过高胰岛素血症的发生胰岛素分泌的胰岛素分泌.这就是LRG1的重点.2 型糖尿病 2 型糖尿病

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