在下的孤独纤维瘤
Thamyres Campos Fonsêca1, Michelle Agostini1, Jefferson Viapiana Paes2
1Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Professor Rodolpho Paulo Rocco, 325, 1º andar, Rio de Janeiro, 21941- 913, Brazil.
Head and neck pathology
|November 26, 2024
概括
在下的罕见的孤独纤维瘤 (SFT) 呈现出侵略性,最初模仿良性状况,但反复出现恶性特征. 这一案例凸显了在面部不对称性和骨损伤中考虑SFT的重要性.
科学领域:
- 口腔和牙面部外科手术
- 病理学 病理学 病理学
- 在瘤学瘤学.
背景情况:
- 孤独纤维性瘤 (SFT) 是一种罕见的纤维细胞起源的细胞间瘤.
- SFTs的特点是特定的遗传变化 (NAB2::STAT6基因融合) 和独特的组织学特征,包括象鹿角的血管系统.
- 虽然SFT可以发生在各种位置,但它们在下部的发生并不频繁,它们的行为可能是不可预测的.
研究的目的:
- 报告一个下中部孤独纤维瘤的病例.
- 描述下SFT的临床,放射和病理学特征.
- 为了强调反复的性质和积极的放射性外观,可以模仿恶性瘤.
主要方法:
- 临床表现和患者病史.
- 放射性评估 (骨稀缺,皮质再吸收).
- 组织病理学检查 (状细胞,原蛋白,鹿角血管).
- 免疫组织化学分析 (CD34,BCL-2,CD99,STAT-6阳性).
主要成果:
- 一名41岁的妇女出现了面部不对称性和疼痛的下质量.
- 组织病理学揭示了一种平淡的状细胞与鹿角血管的增殖.
- 免疫组织化学证实了SFT (CD34 +,Bcl-2 +,CD99 +,STAT-6 +). 免疫组织化学证实了SFT (CD34 +,Bcl-2 +,CD99 +,STAT-6 +).
- 最初的保守治疗导致4年内复发,骨严重受损,恶性瘤类型的放射性特征.
结论:
- 中下SFT可以表现出反复的行为,并呈现出暗示恶性瘤的放射特征.
- 准确的诊断需要临床,放射和详细的组织病理学和免疫组织化学分析.
- 部SFT的管理可能需要积极的外科手术方法,因为潜在的复发和骨破坏.
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