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Updated: Jun 6, 2025

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity
10:10

Development of Stem Cell-derived Antigen-specific Regulatory T Cells Against Autoimmunity

Published on: November 8, 2016

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内源性抗原在自身免疫性关节炎模型中塑造了转录组和TCR谱系

Elizabeth E McCarthy1,2,3, Steven Yu1, Noah Perlmutter1

  • 1Rosalind Russell and Ephraim P. Engleman Rheumatology Research Center, Department of Medicine.

The Journal of clinical investigation
|November 26, 2024
PubMed
概括

在SKG小鼠中缺陷的T细胞信号传递促进了致病性自反应性CD4+T细胞. 内源逆转录病毒破坏耐受性,导致自身免疫性关节炎,但抗逆转录病毒治疗可以制疾病.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.免疫学 免疫学 免疫学T细胞受体受体的 T 细胞受体.宽容是一种宽容.

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