多药耐药的轮溶解性皮肤菌和非皮肤菌会在门诊患者中引起桃菌病
Sajeda Akter1, Parveen Afroz Chowdhury2, Marufatuzzahan3
1Department of Genetic Engineering & Biotechnology, School of Life Sciences, Shahjalal University of Science and Technology, Sylhet, Bangladesh.
Future microbiology
|November 26, 2024
概括
洋基菌病通常是由真菌引起的,皮质植物 (DM) 和非皮质菌模 (NDM) 呈现出越来越多的多药性耐药性. 抗真菌敏感性测试显示对常见药物的耐药性,但对特尔比纳芬化,尼斯塔丁和可纳的敏感性.
科学领域:
- 医学真菌学 医学真菌学
- 抗微生物耐药性 抗微生物耐药性
背景情况:
- 甲状腺炎是一种指甲真菌感染,由皮肤菌 (DM),非皮肤菌模具 (NDM) 和酵母菌引起.
- 了解病因因素及其抗真菌敏感性对于有效治疗至关重要.
研究的目的:
- 识别和确定导致桃菌病的真菌病原体的抗菌谱.
- 评估孤立真菌的解活性 (KA) 和抗真菌耐药性模式.
主要方法:
- 使用形态,文化和生化特征进行真菌鉴定.
- 用青评估的类溶解活性;通过亚格扩散确定的抗生素.
- 通过微稀释确定最小抑制度 (MIC) 和最小杀菌度 (MFC).
主要成果:
- 在男性,脚指甲和商业雇员中,阴茎瘤菌病普遍存在.
- DM,NDM和酵母分别占病例的46%,35%和19%.
- 所有分离物对灰色富尔文和可纳有耐药性; 71%对特尔比纳芬化有敏感性. 多种药物耐药性在DM (84%) 和NDM (46%) 中很高.
结论:
- 多种药物耐药性是 keratinolytic 皮肤菌和非皮肤菌菌引起 onychomycosis 的日益关注的问题.
- 对常见抗真菌药物的有限敏感性需要进一步研究有效的治疗策略.
更多相关视频
09:06Author Spotlight: Photodynamic Therapy as a Novel Approach to Induce Petite Colonies in Drug-Resistant Candida for Antifungal Research
Published on: March 29, 2024
669
08:54Broth Microdilution In Vitro Screening: An Easy and Fast Method to Detect New Antifungal Compounds
Published on: February 14, 2018
18.8K
相关概念视频
Skin Diseases and Disorders
3.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
3.4K
Hand hygiene
3.1K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.1K
Combined Effects of Drugs: Synergism
3.7K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.7K
Fungal Group Zygomycota
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
Diversity of Protists II
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
