使用新型导航器辅助程序促进癌症临床试验的招生:一个跨部门研究
Mahmoud Hossami1, Rhonda Abdel-Nabi1, Farwa Zaib2
1Faculty of Biomedical Science, University of Windsor, Windsor, ON N9B 3P4, Canada.
Current oncology (Toronto, Ont.)
|November 26, 2024
概括
临床试验导航器 (CTN) 计划成功地为患者确定了潜在的癌症临床试验. 该计划有助于试验推和招生,解决癌症护理的关键差距.
科学领域:
- 在瘤学瘤学.
- 临床研究 临床研究
- 医疗信息学 医疗信息学
背景情况:
- 临床试验对于推进癌症治疗和改善患者治疗结果至关重要.
- 在临床试验中招募患者存在重大挑战.
- 临床试验导航器 (CTN) 计划是通过促进临床试验搜索过程来弥合癌症护理旅程的差距而开发的.
研究的目的:
- 评估临床试验导航器 (CTN) 计划在识别和促进癌症患者参加临床试验方面的有效性.
- 在CTN计划中分析影响临床试验转诊率和入学率的因素.
主要方法:
- 该CTN计划利用REDCap调查从2019年3月至2024年7月期间从癌症患者,他们的家人和护理团队中收集患者病史.
- 申请人收到了潜在临床试验的精选清单.
- 关键的成功指标包括临床试验转诊率和入学率.
主要成果:
- 共有445名患有癌症的个人申请了CTN计划.
- 88%的申请人被确定为潜在的试验,平均每名患者进行一项试验.
- 在有可用数据的262名患者中,有27.5%获得了试验转诊,18.1%的转诊患者被录取.
结论:
- 该CTN计划在协助癌症患者进行临床试验搜索方面取得了成功.
- 计划在加拿大各地进一步实施,对患者报告的结果进行评估,并扩大外展.
- 持续的研究是必要的,以了解影响试验转诊和招生因素.
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