怀孕妇女的结果与假体心脏门
Giunai Sefiyeva1, Ulyana Shadrina1, Tatiana Vavilova1
1Almazov National Medical Research Centre, St. Petersburg 197341, Russia.
Journal of cardiovascular development and disease
|November 26, 2024
概括
带有假心 (PHV) 的女性在怀孕期间面临风险. 有效的抗Xa因子控制减少了血栓事件,但产后出血仍然是一个问题,需要调整抗凝剂治疗.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 血栓形成研究研究
背景情况:
- 患有假体心脏门 (PHV) 的女性怀孕存在独特的挑战.
- 管理抗凝血药物对于平衡血栓和出血风险至关重要.
研究的目的:
- 评估PHV怀孕中的血栓和出血并发症.
- 在怀孕,分娩和产后期间识别相关的风险因素.
主要方法:
- 追溯队列研究 (2011年1月至2022年12月) 88个怀孕的77个PHV.
- 机械假肢 (MVP) 和生物假肢 (BVP) 组之间的比较.
- 对怀孕结果,血栓和出血并发症频率的分析.
主要成果:
- 在88个怀孕中,79个活产.
- MVP组:17.2%怀孕期间发生血栓并发症,17.9%产后出血并发症.
- BVP组:4.2%的过渡性缺血性发作;没有产后血栓或出血事件.
结论:
- 有效的抗Xa因子控制减轻了血栓事件.
- 产后出血的高发病率表明需要修订抗凝剂方案和目标水平.
- 尽管存在风险,但在这个队列中没有观察到产妇死亡率.
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