用银处理的丝纤维蛋白支架用于预防关键伤口感染
Federica Paladini1,2, Francesca Russo3, Annalia Masi3
1Department of Experimental Medicine, University of Salento, Via Monteroni, 73100 Lecce, Italy.
Biomimetics (Basel, Switzerland)
|November 26, 2024
概括
丝纤维素支架上的银涂层增强了伤口愈合装置,改善了机械性能,并提供了对常见的伤口细菌如大肠杆菌和P. aeruginosa的抗菌作用.
科学领域:
- 生物材料科学 生物材料科学
- 再生医学是一种再生医学.
- 传染病研究 传染病研究
背景情况:
- 慢性伤口带来严重的感染风险,特别是在老年人,糖尿病患者和肥胖患者身上.
- 越来越多的细菌耐药性限制了治疗伤口感染的治疗选择.
- 丝纤维素支架在伤口愈合中的组织工程方面表现有前途.
研究的目的:
- 开发一种带有复原性和抗菌性质的丝纤维素支架.
- 调查银涂层对用于伤口愈合的丝纤维素支架的影响.
主要方法:
- 丝纤维蛋白脚手架被涂上抗菌银.
- 分析了经过处理的脚手架的化学物理和微生物特性.
- 对大肠杆菌和Pseudomonas aeruginosa进行了抗菌疗效测试.
主要成果:
- 银涂层改善了丝纤维蛋白脚手架的机械性能.
- 经过银处理的脚手架显示出显著的抗菌疗效.
- 对大肠杆菌和抗生素耐药的P. aeruginosa.有效.
结论:
- 涂银的丝纤维素支架为慢性伤口管理提供了一个有前途的双重方法.
- 这一策略增强了再生潜力,同时对抗细菌感染.
- 解决了对先进伤口愈合解决方案的急需问题.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Hand hygiene
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
Cleaning, Sterilization, and Disinfection
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Transmission-based Precautions II: Airborne and Protective Environment
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Standard Precaution
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Handwashing II: Pre-procedure and Initial Procedure Steps
The pre-procedure steps of handwashing include removing jewelry and rolling up sleeves. However, many organizations allow staff to wear wedding rings.
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury. The nails must be short and clean, without nail paint...
The hand washing procedure itself includes the following steps. First, cover cuts, if any, on hands with a waterproof dressing. Cuts and abrasions can become contaminated with bacteria hindering the ability to clean the area thoroughly. In addition, repeated hand washing can worsen an injury. The nails must be short and clean, without nail paint...


