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Updated: Jun 6, 2025

A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes
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A Fluorescent Intravital Imaging Approach to Study Load-Induced Calcium Signaling Dynamics in Mouse Osteocytes

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低,但不高,脉动流体剪切应力影响矩阵细胞外糖蛋白表达,主要通过前骨质母细胞中的整体β子单元

Jianfeng Jin1, Behrouz Zandieh-Doulabi1

  • 1Department of Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, 1081 LA Amsterdam, The Netherlands.

Current issues in molecular biology
|November 26, 2024
PubMed
概括

脉动流体剪切应力 (PFSS) 影响了前骨质母细胞中的整合素表达. 低PFSS独特调节矩阵细胞外糖蛋白 (Mepe) 基因表达,影响骨细胞信号和矿化.

关键词:
整体的α/β子单元.矩阵细胞外的糖蛋白蛋白质.机械载荷 机械载荷是指机械载荷.骨质性分化的骨质性差异化在前骨质细胞前.脉动流体的剪切应力压力.

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