关于生物活性分子和先进微生物管理技术的全面审查
Adil Farooq Wali1, Sirajunisa Talath1, Sathvik B Sridhar2
1Department of Pharmaceutical Chemistry, RAK College of Pharmacy, RAK Medical and Health Sciences University, Ras Al Khaimah 11172, United Arab Emirates.
Current issues in molecular biology
|November 26, 2024
概括
抗菌素耐药性是一个主要的健康威胁. 本综述强调了微生物中的天然化合物作为新抗微生物药物的有前途来源,并讨论了其开发的先进技术.
科学领域:
- 微生物学和药理学 微生物学和药理学
- 自然产品化学 自然产品化学
- 公共卫生 公共卫生
背景情况:
- 越来越多的抗药性微生物菌株的流行率构成了全球重大健康挑战.
- 迫切需要新型抗菌剂来对抗传染病并降低死亡率.
- 微生物代表了一个尚未开发的生物活性分子储存库,具有潜在的抗菌特性.
研究的目的:
- 审查从微生物中提取的天然化合物的重要性,作为新型抗微生物药物的来源.
- 探索用于发现和开发有效抗微生物治疗的先进技术和策略.
- 突出微生物在人类生存和适应环境变化的作用.
主要方法:
- 使用主要科学数据库 (SCOPUS,SCI,PUBMED,ScienceDirect,Medline) 进行全面的文献审查.
- 对各种微生物来源进行分析,以发现抗微生物和抗真菌药物.
- 检查微培养技术和基于微生物的微系统的应用.
主要成果:
- 识别各种微生物来源,产生有希望的抗微生物化合物.
- 对抗微生物药物开发当前和新兴技术的概述.
- 讨论新生物分子和计算方法的潜力.
结论:
- 来自微生物的天然化合物提供了对抗抗菌素耐药性的重要资源.
- 先进的技术和创新的模型系统对于加强新抗微生物药物的开发至关重要.
- 对微生物衍生化合物的进一步研究对于解决抗菌素耐药性的公共卫生危机至关重要.
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