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Updated: Jun 6, 2025

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

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一个准确的半经验模型用于PMT脉冲信号分析

Shuo Li1, Xudong Lyu2, Fei Wang1

  • 1Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, Hubei, China.

PloS one
|November 26, 2024
PubMed
概括

这项研究引入了一种新的半经验数学模型,用于分析来自光倍增管 (PMT) 的闪光脉冲信号. 与现有方法相比,该模型在匹配脉冲信号数据方面提供了更高的准确性.

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Rectangular and Triangular Pulse Function01:19

Rectangular and Triangular Pulse Function

The unit rectangular pulse function is mathematically represented by a rectangular function centered at the origin with a height of one unit. This function is defined by two parameters: T, which specifies the center location of the pulse along the time axis, and τ, which determines the pulse duration.
For example, consider a rectangular pulse with a 5V amplitude, a 3-second duration, and centered at t=2 seconds. This pulse can be expressed using the rectangular function, written as,
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Special considerations while measuring pulse

Assessing a patient's pulse is a fundamental skill in healthcare, but certain situations require special attention:
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Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Pulse01:16

Pulse

When the heart pumps blood out, arterial elastic fibers play a crucial role in sustaining a high-pressure gradient. They expand to accommodate the received blood and then recoil - a process known as the pulse that can be either manually palpated or electronically quantified. Despite a reduction in its effect with increased distance from the heart, elements of the pulse's systolic and diastolic components persist, observable even at the arteriole level.
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Linear Approximation in Time Domain01:21

Linear Approximation in Time Domain

Nonlinear systems often require sophisticated approaches for accurate modeling and analysis, with state-space representation being particularly effective. This method is especially useful for systems where variables and parameters vary with time or operating conditions, such as in a simple pendulum or a translational mechanical system with nonlinear springs.
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