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Updated: Jun 6, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

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全基因组染色体架构预测揭示了基因结构的基础生物物理原理

Michael Chiang1, Chris A Brackley1, Catherine Naughton2

  • 1SUPA, School of Physics and Astronomy, University of Edinburgh, Peter Guthrie Tait Road, Edinburgh EH9 3FD, UK.

Cell genomics
|November 26, 2024
PubMed
概括

我们开发了一种新的模型,即表观遗传高度预测性的异形聚合物 (e-HiP-HoP),用于预测3D染色质结构及其与基因功能之间的联系. 这揭示了染色体组织如何影响基因活性.

关键词:
在这种情况下,染色染色素染色素建模 染色素建模基因组组织组织机械模型是机械模型.聚合物物理 聚合物物理

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