:

Aisling S Carr1,2, Frederick William Vonberg2,3, Shiwen Koay4,2

  • 1Centre for Neuromuscular Diseases, National Hospital for Neurology and Neurosurgery, London, UK Aisling.carr@nhs.net.

Practical neurology
|November 26, 2024
PubMed
概括

免疫检查点抑制剂 (ICI) 增强抗癌免疫力,但可能导致罕见的严重神经毒性. 随着ICI使用的扩大,管理这些不良事件需要多学科的专业知识.

相关概念视频

Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
859
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
26