根据法医住院病人的数据库,日本法医精神病房中抗精神病药物处方的现状和特征
Koji Takeda1, Hiroko Kashiwagi1, Keisuke Takanobu2
1Department of Forensic Psychiatry, National Center Hospital, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan.
Neuropsychopharmacology reports
|November 26, 2024
概括
这项研究调查了日本法医精神病房中精神障碍性精神障碍谱系障碍的精神障碍者使用抗精神病药物的情况. 克洛扎宾和长效注射 (LAI) 经常被处方,克洛扎宾与更高的隔离率有关.
科学领域:
- 法医精神病学 法医精神病学
- 心理药理学 心理药理学
- 精神分裂症谱系障碍 精神分裂症谱系障碍
背景情况:
- 精神药物治疗对于精神障碍犯罪者 (MDO) 具有精神分裂症谱系障碍至关重要.
- 在日本法医精神病学环境中使用抗精神病药物的大规模数据有限.
研究的目的:
- 调查日本法医精神病房中MDO患有精神分裂症谱系障碍的抗精神病药物的现状.
- 为了比较用克洛扎宾,长效注射剂 (LAI) 和其他抗精神病药物治疗的患者的特征.
主要方法:
- 分析了全国32个法医精神病房的出院数据 (2019年9月至2021年12月).
- 包括患有精神分裂症谱系障碍的MDO在出院时处方精神药物.
- 克洛扎宾,LAI和其他药物组的比较.
主要成果:
- 分析了362个MDO;克洛扎宾和LAI处方率分别为23.2%和24.9%.
- 抗精神病药物多药剂使用率为37.8%.
- 克洛扎组的隔离率较高 (46.4%),住院时间较长 (1758天),多药性治疗率较低 (4.8%). 奥兰沙平是最常见的药物.
结论:
- 该研究提供了对日本法医精神病房中MDOs目前抗精神病药物处方实践的见解.
- 需要进一步的研究,以了解这些药物治疗策略的预后意义.
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