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CD8+组织内存T细胞与年龄相关的下降损害了抗瘤免疫力

Siyu Pei1,2, Xiuyu Deng2, Ruirui Yang3

  • 1Department of Thoracic Surgical Oncology, Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Nature aging
|November 26, 2024
PubMed
概括

衰老会通过阻碍组织内存T (TRM) 细胞的产生,损害CD8+ T细胞的抗瘤免疫力. 用IBFAR2准BFAR可以恢复TRM形成,并增强老年小鼠的抗瘤活性.

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