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中国患者急性甲型大动脉剖析ICU再入院的预测模型:一项回顾性研究
Hong Ni1,2, Yanchun Peng1, Qiong Pan1
1Department of Nursing, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China.
BMC medical informatics and decision making
|November 26, 2024
概括
一种新的预测模型有助于识别患有急性A型大动脉解剖 (ATAAD) 的患者,这些患者有重症监护室 (ICU) 重收的高风险. 关键预测因素包括年龄较大,BMI较高,气管切除术,连续置换疗法和较长的初始ICU停留时间.
科学领域:
- 心血管外科心血管外科
- 关键护理医学 关键护理医学
- 医学预测建模医学预测建模
背景情况:
- 对于急性A型大动脉剖析 (ATAAD) 患者,重症监护室 (ICU) 的再接收是一个重大的临床挑战.
- 再接收与增加的死亡率和医疗保健成本有关.
研究的目的:
- 开发和验证一个基于名录的预测模型,用于ATAAD患者的ICU再入院.
- 在这个人群中确定与ICU再接收相关的独立风险因素.
主要方法:
- 846名ATAAD患者的回顾性分析 (2014年5月 - 2021年10月).
- 后勤回归用于识别ICU再接收的独立风险因素.
- 使用Hosmer-Lemeshow测试,校准曲线和接收器操作特征曲线 (AUC) 下的面积的模型验证.
- 通过决策曲线分析 (DCA) 评估的临床效用.
主要成果:
- 6.7%的ATAAD患者经历了ICU再入院.
- 预测ICU再入院的预测因素包括年龄≥65岁,BMI≥28kg/m2,气管切割,连续脏替代疗法 (CRRT) 和较长的初始ICU停留时间.
- 预测模型的AUC达到0.837,并显示出良好的适应性 (H-L测试P=0.519) 和临床效用 (DCA).
结论:
- 一个经过验证的基于名录的预测模型可以有效地评估ATAAD患者的ICU再接收风险.
- 早期识别高风险患者有助于及时进行临床干预.
- 该模型对临床医生管理ATAAD患者在ICU出院后的临床医生提供了实际的实用性.
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