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中国人群中高尿血和异常深静脉血栓症之间的性别特异关系:一个病例控制研究
Xiaoyu Cheng1,2,3, Fei Yan2,3, Xue Xiaomei2,3
1Department of Endocrinology, Qilu Hospital of Shandong University, No. 107 Cultural West Road, JiNan, 250012, China.
Thrombosis journal
|November 26, 2024
概括
血清尿酸水平高的超尿血症,显著增加了异常性深静脉血栓塞 (DVT) 的风险. 这种关联在女性中尤为明显,突出了基于性别的DVT危险因素.
科学领域:
- 心血管医学 心血管医学
- 代谢障碍 代谢障碍 代谢障碍
- 流行病学 流行病学
背景情况:
- 高尿路血症与二次深静脉血栓形成 (DVT) 有关.
- 鉴于性别和血清尿酸 (SUA) 水平,异常性DVT的危险因素需要进一步调查.
研究的目的:
- 检查高尿血和异常下肢DVT之间的关系,重点关注性别差异.
主要方法:
- 对4299名接受下肢超声波检查的患者进行了回顾性分析.
- 基线SUA水平和DVT和对照组之间的数据的比较,按性别分层.
- 多变量逻辑回归以评估高尿血和异常性DVT之间的关联,调整混因子.
主要成果:
- 与对照人群相比,患有异常性DVT的患者的SUA水平显着更高,与所有患者和每个性别相比,高尿素血的比例更高.
- 超尿路血症与2.643倍增加的异常下肢DVT的风险有关.
- 妇女的风险要高得多,高尿路血症增加了7.482倍的风险.
结论:
- 超尿路血是中国人群中异常性下肢DVT的重要危险因素.
- 超尿血和异常性DVT之间的关联在女性患者中特别强烈.
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