托尔样受体3介导的干扰素-β产生被oncostatinm和更广泛的上皮层-介质细胞过渡程序抑制

Noah M Chernosky1,2, Ilaria Tamagno1,2, Kelsey L Polak1,2

  • 1Department of Pathology Case, Western Reserve University, Cleveland, OH, 44106, USA.

PubMed
概括

在三阴性乳腺癌 (TNBC) 中, Kostatin M (OSM) 通过抑制通类受体3 (TLR3) 抑制了干扰素β (IFN-β) 的产生. 向OSM可能会恢复IFN-β信号传递并改善治疗反应.

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