大动脉硬化不是一种良性发现,而是与不良的心血管结果相关的渐进性疾病
Jeong Hun Seo1, Kwang Jin Chun1, Bong-Ki Lee1
1Division of Cardiology, Department of Internal Medicine, Kangwon National University Hospital, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.
Journal of cardiovascular imaging
|November 27, 2024
概括
大动脉硬化进展显著增加了心血管死亡风险. 监测AVS进展的患者对于更好的心血管结果至关重要.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 血管生物学 血管生物学
背景情况:
- 大动脉硬化症 (AVS) 与动脉样硬化的风险因素相同.
- 在AVS进展和心血管 (CV) 风险之间的联系是研究不足.
研究的目的:
- 根据AVS进展,调查患者的心血管结果.
- 为了确定AVS进展的预测因素.
主要方法:
- 包括2,901名患有AVS的患者和连续回声心脏图 (间隔≥1年).
- 主要结局定义为心血管死亡,心肌梗塞,中风或再血管.
- 使用逐步回归分析了AVS进展的预测因素.
主要成果:
- 15.1%的AVS患者在平均3.9年内进展为大动脉狭窄.
- 静脉动脉硬化进展与老年,心房动,外围动脉疾病和左心室质量指数增加有关.
- 患有AVS进展的患者具有显著更高的不良心血管事件发生率 (P < 0.0001).
- 动脉动脉系统进展是心血管死亡率的独立预测因素 (HR, 1.33; 95% CI, 1.10-1.61).
结论:
- 动脉动脉系统的进展是心血管死亡的独立风险因素.
- 患有AVS进展的患者可能受益于加强心血管风险管理和监测.
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