在疑似感染性内心炎患者中持续发烧的预测因素:超越常规思维
Elisavet Stavropoulou1, Pierre Monney2, Georgios Tzimas2
1Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
概括
怀疑感染性内心炎 (IE) 的持续发烧与特定感染,如脊髓炎和腹部感染有关. 早期适当的治疗和源控制是减少IE患者发烧持续时间的关键.
科学领域:
- 传染性疾病 传染性疾病
- 临床医学 临床医学
- 微生物学 微生物学
背景情况:
- 发烧是传染性内心炎 (IE) 的常见症状,但其持续时间和预测因素尚不清楚.
- 识别与持续发烧相关的因素对于管理疑似IE病例至关重要.
研究的目的:
- 在疑似感染性内心炎的患者中确定持续发烧的预测因子.
- 分析与这些患者早期发热相关的因素.
主要方法:
- 在洛桑大学医院 (2014-2023) 进行的一项回顾性研究包括发烧患者,怀疑IE.
- 持续发烧被定义为在开始抗菌药物治疗后至少持续96小时.
主要成果:
- 持续发烧发生在19%的可疑IE发作中. 在确诊的IE病例中,15%的人患有持续发烧.
- 持续发烧的预测因素包括持续的细菌病/淋巴病,脊髓炎和腹腔内感染.
- 早期的分发与特定的细菌感染 (菌株,肠杆菌),及时的源控制和适当的抗菌治疗有关.
结论:
- 怀疑IE的持续发烧与脊髓样炎,不适当的抗菌药物治疗和缺乏源控制有关.
- 在确诊的IE患者中,持续发烧与本地骨和关节感染有关.
相关概念视频
Endocarditis II: Clinical features and Diagnostic Tests
2
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
2
Endocarditis I: Introduction
2
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
2
Endocarditis III: Medical Management
2
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
2
Myocarditis II: Clinical features and Diagnostic Tests
2
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
2
Patterns of Fever
2.4K
Before understanding the types and patterns of fever, it is essential to know its phases.
2.4K
Pericarditis II: Clinical features and Diagnostic Tests
3
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
3


