准备,特征,稳定性和In Vitro释放一个豆蛋白纤维基铁强化剂通过自组装
Xiaoting Chen1, Jiang Yi1, Zhen Wen1
1Shenzhen Key Laboratory of Food Macromolecules Science and Processing, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060, China.
Foods (Basel, Switzerland)
|November 27, 2024
概括
铁豆蛋白纤维 (Fe-Fib PP) 纳米复合物增强铁的稳定性和生物可用性,显示出作为营养有效的铁补充剂的巨大潜力. 与传统的铁纳米颗粒相比,这种创新的铁强化剂提供了更好的分散性和铁含量.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物材料科学 生物材料科学
- 营养生物化学 营养生物化学
背景情况:
- 缺铁仍然是一个重要的全球健康问题,需要开发有效的铁强化剂.
- 传统的铁补充剂往往由于稳定性差,生物可用性低,以及不良的感觉特性而受到影响.
- 豆蛋白纤维为开发新型铁输送系统提供了一个有希望的自然基质.
研究的目的:
- 制造和表征铁豆蛋白纤维 (Fe-Fib PP) 纳米复合材料,以提高铁的稳定性和生物可访问性.
- 评估Fe-Fib PP作为营养应用中有效的铁强化剂的潜力.
- 为了比较Fe-Fib PP与常规铁纳米颗粒 (Fe-Nano) 的性能.
主要方法:
- 豆蛋白纤维通过在pH值2.0下对豆蛋白分离物进行热处理来制备.
- 铁离子被纳入豆蛋白纤维,形成Fe-Fib PP纳米复合材料.
- 描述包括评估减少功率,分散性,在各种条件下的稳定性,以及使用X射线光电子谱学 (XPS) 的铁 (II) 含量.
- 在实验室中确定了铁的生物可访问性.
主要成果:
- 豆蛋白纤维的减少能力随着化时间的增加而增加,增强了铁的结合.
- 与Fe-Nano相比,Fe-Fib PP表现出明显更高的分散性和铁稳定性.
- 在XPS分析中证实Fe-Fib PP的Fe (II) 含量高于Fe-Nano (56.05%) 的Fe (II) 含量 (70.75%).
- 当使用PP纤维作为载体时,Fe (II) 的生物可访问性从42.7%提高到62.8%.
结论:
- 与Fe-Nano.相比,Fe-Fib PP纳米复合材料表现出优越的稳定性,可分散性和铁 (II) 含量.
- 豆蛋白纤维作为载体的使用显著提高了铁的生物可访问性.
- Fe-Fib PP是一种有前途且有效的铁强化剂,可以改善营养铁摄入量.
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