在医疗成像中对有的对比介质的比较安全概况和使用模式
Yu Ri Shin1, Seo Yeon Youn1, Hokun Kim1
1Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 07345, Republic of Korea.
Diagnostics (Basel, Switzerland)
|November 27, 2024
概括
第二线含的对比介质 (ICM) 显示出显著更高的过敏反应 (HSR) 率. 量身定制的前期治疗方案有效降低了中度的HSR,提高了计算机断层扫描 (CT) 影像中的患者安全.
科学领域:
- 放射学和成像学 放射学和成像学
- 药物监督 药物监督 药物监督
- 患者安全 患者安全
背景情况:
- 无离子离子对比介质 (ICMs) 对于计算机断层扫描 (CT) 非常重要.
- 了解不同ICM的使用模式和过敏反应 (HSR) 概况对于优化患者安全至关重要.
- 之前的研究表明ICM中HSR率的变化,需要进一步调查.
研究的目的:
- 在CT扫描中分析六种非离子ICM的使用模式和HSR概况.
- 为了比较不同ICM的HSR的发病率和严重程度.
- 评估前期治疗方案对HSR率的影响,并为基于证据的对比剂选择提供信息.
主要方法:
- 从2020年1月到2022年12月,对248,209次CT扫描进行了回顾性审查.
- 基于使用率和HSR数据的六种ICM (iomeprol,iohexol,ioversol,iopromide,iodixanol,iobitridol) 的比较.
- 评估预治疗方案的强化和季度HSR趋势.
主要成果:
- 总共有1603个HSR (0.65%) 被记录下来,主要是轻度 (86.2%).
- 第二线药物 (iobitridol,iodixanol) 显示HSR比第一线药物高7-8倍.
- 一个修改后的前期治疗方案显著降低了中度HSRs (p=0.0075),在Q1出现了较高率的趋势,在Q3严重的HSRs显著增加 (p=0.033).
结论:
- 二线ICM与显著更高的HSR率有关,强调了谨慎的选择.
- 强化前期治疗方案在缓解中度HSR方面是有效的,提高了患者的安全.
- 对与ICM相关的HSR机制的进一步研究是有必要的,以改进临床管理策略.
相关概念视频
Radiological Investigation I: X-ray and CT
214
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
214
Imaging Studies I: CT and MRI
197
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
197
Imaging Studies for Cardiovascular System III: X-Ray
145
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
145
Imaging Studies for Cardiovascular System V: CT
3
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
3
Imaging Studies for Cardiovascular System IV: CMRI
6
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
6
Imaging Studies II: Positron Emission Tomography and Scintigraphy
86
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
86


