在初始内镜逆行性胆管细胞造影中口胆管镜的可行性,用于恶性胆管紧张症
Yuichi Suzuki1,2, Tomohiro Ishii3, Haruo Miwa2
1Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.
Diagnostics (Basel, Switzerland)
|November 27, 2024
概括
在初始内镜逆行性胆管松造影 (ERCP) 期间的口腔胆管镜检查 (POCS) 对于恶性胆管狭窄是可行的. 这种新技术的安全性和有效性与标准ERCP相比,没有先前排水,有助于诊断.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 在瘤学瘤学.
背景情况:
- 口腔胆道透视 (POCS) 对于评估恶性胆道狭窄至关重要.
- 在POCS前的胆汁排水可能会损害诊断的准确性.
研究的目的:
- 评估在恶性胆管狭窄的初始ERCP期间使用新型CHF-B290胆管镜进行POCS的可行性.
- 评估这种方法的安全性和有效性.
主要方法:
- 回顾性多中心研究 (2018年1月 - 2022年3月).
- 进行初始ERCP的POCS患者 (POCS组) 与没有POCS (非POCS组) 的患者进行比较.
- 利用CHF-B290的灌系统来预防POCS后的胆管炎;主要终点:ERCP后的胆道感染.
主要成果:
- 在POCS组中有53名患者,在非POCS组中有94名患者.
- 在ERCP后的胆道感染率没有显著差异 (1.9%与5.3%,p=0.42).
- 胰腺炎和其他并发症的发病率相似;POCS组的整体并发症率为9.4%,非POCS组为13% (p=0.60).
结论:
- 对于恶性胆道狭窄的初始ERCP期间的POCS是可行的.
- 在CHF-B290胆管镜可以安全地使用,没有事先胆管排水.
- 与标准ERCP相比,这种方法不会增加并发症的风险.
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