在癌症治疗中利用ROS-TME轴
Kostas A Papavassiliou1, Amalia A Sofianidi2, Vassiliki A Gogou1
1First University Department of Respiratory Medicine, 'Sotiria' Chest Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Antioxidants (Basel, Switzerland)
|November 27, 2024
概括
自20世纪初以来,人们就知道有反应性氧物种 (ROS). 这项研究探讨了它们在生物系统中的复杂作用.
科学领域:
- 生物化学和分子生物学
- 细胞生物学 细胞生物学
- 氧化压力研究研究 氧化压力研究
背景情况:
- 反应性氧物种 (ROS) 首次在20世纪初被发现.
- 它们作为信号分子和破坏性剂的双重作用是研究的关键领域.
- 了解ROS对于破译细胞过程和疾病机制至关重要.
相关概念视频
The Tumor Microenvironment
6.5K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.5K
Targeted Cancer Therapies
7.5K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
7.5K


