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Updated: Jun 6, 2025

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引发炎症的工程巨细胞 (MacTriggers) 增强免疫检查点抑制剂的反应性 仅在瘤组织中

Kenta Tanito1, Teruki Nii1,2, Kanae Wakuya1

  • 1Graduate School of Systems Life Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.

Cancers
|November 27, 2024
PubMed
概括

工程化巨细胞 (MacTriggers) 通过调高瘤中的免疫检查点来增强抗PD-1疗法. 这种组合在没有全身副作用的耐药模型中协同抑制瘤生长,为癌症治疗提供了一种新的策略.

关键词:
阿尔基纳1 1免疫检查点抑制剂免疫检查点抑制剂巨细胞是一个巨细胞.编程细胞死亡-1-1三重阴性乳腺癌是什么瘤死亡因子-α

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