相关实验视频

Updated: Jun 6, 2025

Basophil Activation Test for Allergy Diagnosis

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

儿童喘和食物过敏之间的关系

Daniela Cunico¹, Giuliana Giannì¹, Sara Scavone¹

¹Clinica Pediatrica, Department of Medicine and Surgery, University of Parma, 43125 Parma, Italy.

Children (Basel, Switzerland)

|November 27, 2024

概括

儿童喘和食物过敏有共同的危险因素,可以相互恶化. 了解它们之间的联系是改善这些常见过敏疾病治疗的关键.

科学领域:

儿科过敏和免疫学
呼吸系统医学呼吸系统医学

背景情况:

喘和食物过敏是普遍存在的儿童过敏疾病,具有共同的危险因素,如阿托皮和T2炎症.
患有食物过敏的儿童患喘的风险更高,尤其是在生命早期.
同时存在的喘和食物过敏会增加严重恶化,住院和死亡的风险.

研究的目的:

探索儿童中喘和食物过敏之间的复杂关系.
突出伴随性疾病对疾病严重程度和管理的影响.
讨论当前和新兴的治疗策略来管理这些相互关联的过敏疾病.

主要方法:

对喘和食物过敏的流行病学,风险因素和临床表现现的现有文献的审查.
分析病理生理联系和共享的炎症途径.
评估当前的管理策略,包括避免过敏原,紧急治疗和免疫疗法.
探索新的治疗方法,如生物药物.

主要成果:

共同的风险因素和T2炎症途径将喘和食物过敏联系在一起.
对食物过敏原的暴露可以在敏感的个体中引发呼吸系统症状.
伴随性疾病显著增加了严重喘恶化和不良结果的风险.
奥马利祖马布在改善喘控制和过敏原耐受性方面表现有前途,单独或与口服免疫治疗一起使用.

结论:

有效管理喘和食物过敏需要了解它们的复杂相互作用.
避免饮食和紧急上腺素仍然是食物过敏的主要治疗方法.
口服免疫疗法和像奥马利祖马布这样的生物疗法为管理并发性疾病和改善患者结果提供了新的途径.

关键词:

过敏的三月过敏的三月过敏反应是一种过敏反应.喘喘是一种生物学的生物学.孩子们的孩子们的孩子们的孩子们.食物过敏食物过敏在Omalizumab上使用.口服免疫疗法是口服免疫疗法.

更多相关视频

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

相关概念视频

Asthma-I: Introduction

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...

Asthma: Pathogenesis and Management

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

Asthma-II: Pathophysiology and Classification

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:

Asthma-III: Symptoms and Complications

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma

Asthma-IV: Diagnostic and Management

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...