肠道微生物组-宿主遗传学共同进化通过调节精选品种肉的能量和脂质代谢来塑造肥胖
Guangqi Gao1,2,3, Yangbo Jiao1,2,3, Lai-Yu Kwok1,2,3
1Key Laboratory of Dairy Biotechnology and Engineering, Ministry of Education, Inner Mongolia Agricultural University, Hohhot 010018, China.
Animals : an open access journal from MDPI
|November 27, 2024
概括
主体遗传和肠道微生物组相互作用,影响肉的腹部脂肪沉积. 选择性育种改变了微生物组成和宿主基因,影响了能量代谢和脂肪水平.
科学领域:
- 动物科学动物科学
- 遗传学 遗传学 是一个
- 微生物学 微生物学
背景情况:
- 优化腹部脂肪沉积是肉生产和肉质的关键.
- 主体遗传和肠道微生物组是影响脂肪代谢的关键因素.
研究的目的:
- 研究宿主遗传学和肠道微生物在调节腹部脂肪沉积中的相互作用作用.
- 为了比较脂肪线和瘦线肉之间的肠道微生物组和全基因组概况.
主要方法:
- 选择性繁殖肉的15代不同的腹部脂肪水平.
- 肠道微生物组组成和宿主全基因组概况的比较分析.
- 微生物功能通路的元基因组学分析.
主要成果:
- 在相同的条件下,脂肪线和瘦线之间肠道微生物群的显著差异.
- 瘦肉的乳酸菌增加和致病细菌减少,能量代谢途径丰富.
- 在瘦肉中观察到基因组变异,包括脂代谢基因中的SNP.
结论:
- 主体微生物群相互作用显著影响选择性养的腹部脂肪沉积表型.
- 肠道微生物组和宿主基因的共同进化对于家禽生产效率和肉质量至关重要.
- 研究结果为养和基于微生物组的策略提供了洞察力,以管理家禽的脂肪.
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