来自哥伦比亚的一组患者的甲酸莫菲蒂尔的处方模式
Manuel Enrique Machado-Duque1,2, Andrés Gaviria-Mendoza1,2, Luis Fernando Valladales-Restrepo1,2
1Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia, Universidad Tecnológica de Pereira-Audifarma S.A., Pereira 660003, Risaralda, Colombia.
Healthcare (Basel, Switzerland)
|November 27, 2024
概括
哥伦比亚患者主要使用mycophenolate mofetil治疗全身性红斑狼 (SLE) 和其他类风湿性疾病,通常是组合疗法,剂量低于推剂量.
科学领域:
- 药理学 药理学是指药理学的学科.
- 类风湿病学 类风湿病学
- 移植医学 移植医学 移植医学
背景情况:
- 菌酸莫菲蒂尔是预防固体器官移植排斥的关键免疫抑制剂.
- 它也用于自身免疫性疾病,如全身性红斑狼 (SLE).
研究的目的:
- 为了研究哥伦比亚患者的mycophenolate mofetil的处方模式.
- 分析与其使用相关的社会人口学,临床和药理学变量.
主要方法:
- 横截面研究设计. 截面研究设计.
- 从2021年至2022年之间从药物发行数据库中收集的数据.
- 参与分析了979名接受mycophenolate mofetil的患者.
主要成果:
- 系统性红斑狼 (SLE) 是最常见的表示 (39.1%).
- 菌酸莫菲蒂尔经常用于组合疗法 (32.9%) 和经常与多种药物 (76.2%).
- 服用的平均剂量是每日定义剂量的0.75倍.
结论:
- 在哥伦比亚,mycophenolate mofetil主要用于SLE和其他类风湿病.
- 组合疗法是一种常见的治疗策略.
- 处方剂量通常低于推水平.
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