高通量废水样本处理用于传染病监测的叙述性审查:挑战,进展和未来的机会
Bhuvanesh Kumar Shanmugam1, Maryam Alqaydi1, Degan Abdisalam1
1RASID Laboratory, M42 Healthcare, Abu Dhabi P.O. Box 4200, United Arab Emirates.
International journal of environmental research and public health
|November 27, 2024
概括
基于废水的流行病学 (WBE) 提供了强大的社区健康查,但面临着挑战. 解决病原体生存,矩阵变异性和标准化是释放WBE在流行病检测方面的全部潜力的关键.
科学领域:
- 环境科学 环境科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 在COVID-19大流行期间,基于废水的流行病学 (WBE) 对于跟踪感染率和变种至关重要.
- 它在监测传染病方面的潜力得到了认可,扩大了社区卫生监测.
- 然而,WBE的全部能力目前受到几个关键因素的限制.
研究的目的:
- 审查阻碍WBE在社区健康查中的广泛采用挑战.
- 探索成本影响,过程自动化和WBE的未来前景.
- 为研究废水监测提供参考资料,以早期发现流行病.
主要方法:
- 进行了全面的文献调查.
- 根据特定的关键词选择了相关的同行评审文章.
- 审查的重点是WBE的挑战,成本,自动化和前景.
主要成果:
- 确定的主要挑战包括污水中的病原体生存,废水矩阵异质性,采样不一致以及缺乏标准化方法.
- 分析技术的可变灵敏度也会影响WBE的可靠性.
- 讨论了成本影响和流程自动化机会.
结论:
- 克服目前的局限性对于实现WBE在全面社区健康查方面的全部潜力至关重要.
- 方法的标准化和对废水中病原体行为的更好理解至关重要.
- 在早期疫情检测和公共卫生监测方面,WBE具有显著的前景.
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