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在精神分裂症中,可以将非侵入性脑刺激与基于证据的心理社会干预相结合吗? 一个批判性的审查

Jacopo Lisoni¹, Gabriele Nibbio², Antonio Baglioni²

¹Department of Mental Health and Addiction Services, ASST Spedali Civili of Brescia, 25123 Brescia, Italy.

|November 27, 2024

概括

将基于证据的心理社会干预 (EBPI) 与非侵入性脑刺激 (NIBS) 结合起来,显示出精神分裂症治疗的早期前景,特别是在负面和认知症状方面. 需要更多的研究来证实这些发现并改善患者的治疗结果.

科学领域:

精神病学是一个精神病学.
神经科学是一个神经科学.
临床心理学临床心理学

背景情况:

精神分裂症的治疗通常需要多模式的方法,结合药理和非药理干预措施.
基于证据的心理社会干预 (EBPI) 和非侵入性脑刺激 (NIBS) 对解决未满足的临床需求,特别是精神分裂症患者 (PLWS) 的负面和认知症状充满希望.

研究的目的:

审查关于EBPI和NIBS联合使用治疗精神分裂症的现有文献.
评估关于结合这些非药物干预措施的疗效的研究现状.

主要方法:

对研究EBPIs和NIBS在精神分裂症患者中的组合进行了系统审查.
对11项审查研究进行分析,以评估治疗结果.

主要成果:

结合EBPI和NIBS治疗精神分裂症的领域还处于新生阶段,研究有限,结果分歧.
新出现的证据表明,结合重复性跨磁刺激 (rTMS) /间歇性甲基突破刺激 (iTBS) 的认知补救可能有好处,尽管结果不确定.
高频rTMS与家庭干预相结合显示出更有前途的初步发现.
认知激活与跨直流刺激 (tDCS) 相结合,表明有改善工作记忆的潜力.

结论:

在精神分裂症治疗中EBPI和NIBS的组合是一个需要进一步研究的新兴领域.
方法的改进是必要的,以加强证据基础和指导未来的研究在这个领域.

关键词:

这些都是NIBS.认知障碍是一种认知障碍.认知补救是指认知补救.在ITBS中,ITBS是ITBS.综合治疗综合治疗综合治疗负面的症状负面的症状心理社会干预措施心理社会干预 rTMSMS是因为 tDCSCS 是一个很好的方法.

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