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Updated: Aug 16, 2026

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基于超级计算机的虚拟查脱氧核糖核酸甲基转移酶1抑制剂作为新型抗癌剂

Lara Johanna Friedrich1, Axel Guthart1, Min Zhou1

  • 1Department of Pharmaceutical Biology, Institute of Pharmaceutical and Biomedical Sciences, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany.

International journal of molecular sciences
|November 27, 2024
PubMed
概括

研究人员发现化合物4,一种新的DNA甲基转移酶1 (DNMT1) 抑制剂,通过抑制瘤细胞生长,迁移和诱导亡,显示出显著的抗癌活性.

关键词:
通过DNA甲基化.癌症 癌症 癌症 癌症 癌症表观遗传学是指表观遗传学.分子对接和模拟的模拟.虚拟的药物查是虚拟的药物查.

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