相关实验视频

Updated: Jun 6, 2025

Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles
06:58

Evaluation of LC3-II Release via Extracellular Vesicles in Relation to the Accumulation of Intracellular LC3-positive Vesicles

Published on: October 18, 2024

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在神经退行性疾病中,TDP-43与其他致病蛋白的联合聚合及其共同病理

Lei-Lei Jiang1, Xiang-Le Zhang1,2, Hong-Yu Hu1

  • 1Key Laboratory of RNA Innovation, Science and Engineering, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.

International journal of molecular sciences
|November 27, 2024
PubMed
概括

病理性蛋白质聚合是神经退行性疾病 (NDD) 的标志,通常涉及多种蛋白质,如TDP-43. 与其他蛋白质共同聚合的TDP-43加剧了NDD,提供了新的治疗见解.

关键词:
在TDP-43病理学方面,协同聚合是一种协同聚合.共同病理学的共同病理.神经退行性疾病是一种神经退行性疾病.这是一种致病性蛋白质.

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