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Updated: Jun 6, 2025

Identification of Kinase-substrate Pairs Using High Throughput Screening
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全长Src激酶的结构及其关键酸化状态:分子动力学研究研究

Maria A Strelkova1, Anna P Tolstova1, Vladimir A Mitkevich1

  • 1Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 119991 Moscow, Russia.

International journal of molecular sciences
|November 27, 2024
PubMed
概括

这项研究揭示了全长的Src激酶结构,这对细胞代谢和阿尔茨海默氏症等疾病至关重要. 在pY419的酸化激活了Src,增加了它的运动,而pY530则抑制了它,保持了紧的形式.

关键词:
雷赫特 医学博士 医学博士这就是 SH4UD.这就是Src 激酶.蛋白质的酸化是蛋白质的酸化.蛋白质结构 蛋白质结构这是一种原始原基因.

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