在晚期黑色素瘤中,ICOSLG与抗PD-1和同时抗组胺药物治疗反应有关

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Updated: Jun 6, 2025

Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence
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Semi-automatic PD-L1 Characterization and Enumeration of Circulating Tumor Cells from Non-small Cell Lung Cancer Patients by Immunofluorescence

Published on: August 14, 2019

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Domenico Mallardo1, Mario Fordellone2, Margaret Ottaviano1

  • 1Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale", Via Mariano Semmola, 53, 80131 Naples, Italy.

International journal of molecular sciences
|November 27, 2024
PubMed
概括

抗组胺剂塞蒂里辛 (cetirizine) 改善了接受免疫治疗的转移性黑色素瘤患者的治疗结果. 高ICOSLG基因表达预测了对 cetirizine 结合检查点抑制剂的反应,这表明它是一种预测性生物标志物.

关键词:
生物标志物生物标志物这种药物是 cetirizine.检查点抑制抑制检查点的抑制这是皮肤黑色素瘤.

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