风险因素分析,包括ICU入院和肺切除术后生存的炎症标记
Mediha Turktan1, Ersel Gulec1, Alper Avcı2
1Department of Anesthesiology and Reanimation, Faculty of Medicine, Cukurova University, 01330 Adana, Turkey.
Medicina (Kaunas, Lithuania)
|November 27, 2024
概括
内心肺切除术和术后并发症预测了重症监护室 (ICU) 的入院情况. 手术前的炎症标志物和手术并发症与肺切除术后的死亡率有关.
科学领域:
- 心胸外科手术 心胸外科手术
- 外科手术的结果
- 炎症标记物 炎症标记物
背景情况:
- 肺切除术是一种主要的手术手术,具有显著的相关发病率和死亡率.
- 确定重症监护室 (ICU) 入院和生存的预测因素对于优化患者管理至关重要.
- 手术前的炎症参数可能会影响大胸部手术后的结果.
研究的目的:
- 评估手术前炎症标志物与在肺切除术后需要接受ICU治疗之间的关联.
- 确定肺切除术后短期 (28天) 和中期 (90天) 死亡的风险因素.
- 评估特定的外科手术技术和手术内事件对患者结果的影响.
主要方法:
- 在2016年12月至2022年1月期间接受了肺切除术的207名成年患者的回顾性分析.
- 从电子医疗记录中收集数据,包括手术前的实验室值和手术内/术后事件.
- 采用多变量分析来确定ICU入院和死亡率的独立预测因素.
主要成果:
- 在接受ICU治疗的患者中观察到手术前白蛋白降低和更高的输血需求.
- 内心肺切除术和术后并发症是ICU入院的独立预测因素.
- 与28天死亡率相关的因素包括袖口/心周肺切除术,血管损伤,机械通风,功能衰竭,败血症,呼吸功能衰竭,肺炎,输血,BUN升高和肌素.
- 术前较高的中性粒细胞与淋巴细胞比率 (NLR),肌素,袖口/心内肺切除术,机械通风,血管损伤,败血症,呼吸衰竭和逆侧肺炎与90天死亡率有关.
结论:
- 内心肺切除术和术后并发症是肺切除术后ICU入院的重要预测因素.
- 手术前的炎症标志物 (NLR,BUN,肌素) 和手术因素 (袖子/心脏内手术,手术内并发症,输血) 与死亡风险增加有关.
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