脑超声波在严重疾病的败血症患者:一个范围审查
Giada Cucciolini1, Irene Corda1, Francesco Forfori1
1Department of Surgical, Medical, Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.
Journal of clinical medicine
|November 27, 2024
概括
大脑超声波显示,通过检测改变的大脑输液,对监测败血症相关脑病变 (SAE) 有希望. 然而,目前的证据有限,缺乏指导治疗和预测结果的标准化.
科学领域:
- 关键护理医学 关键护理医学
- 神经学 神经学
- 医疗成像医学成像
背景情况:
- 败血症相关脑病变 (SAE) 是一种常见的并发症,具有显著的死亡率和神经缺陷.
- 脑部监测对于治疗败血症患者至关重要,但需要使用非侵入性方法.
- 大脑超声波 (美国) 为评估大脑状态提供了一种非侵入性方法.
研究的目的:
- 审查关于败血症中脑 perfusion 改变的文献.
- 评估大脑US在指导复苏工作中的作用.
- 为了评估大脑US对败血症神经学结果的预测价值.
主要方法:
- 对三个数据库进行了范围审查.
- 包括的研究集中在ICU的成人败血症或败血性休克患者身上.
- 搜索随机对照试验,临床试验,观察性研究和系统性审查.
主要成果:
- 包括34项研究,主要是观察性 (85%).
- 败血症中脑血流 (CBF) 的改变显示出不同的结果 (增加,正常或减少).
- 大脑自调节 (CAR) 障碍很常见,特别是在败血症的早期,并且与糟糕的结果有关,尽管影响的清晰度缺乏.
结论:
- 大脑US可以检测到血症中大脑 perfusion 变化,这表明其潜在的实用性.
- 目前关于美国脑毒症的证据基础有限,缺乏标准化,需要进一步研究.
- 需要更强大的标准化研究来确定大脑US以指导复苏和预测SAE的结果.
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