相关实验视频
Updated: Jun 6, 2025

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.8K
危急病患者的血糖变化和死亡率之间的关联:一个多中心前性观察性研究
Ömer Emgin1, Mehmet Yavuz2, Adem Şahin3
1Department of Intensive Care Unit, Tepecik Training and Research Hospital, Konak, Izmir 35020, Turkey.
Journal of clinical medicine
|November 27, 2024
概括
危急病患者的高血糖变化率 (GV),通过24小时内变化系数 (CV) 测量,独立预测28天死亡率. 平均葡萄糖差异 (MGD) 也与死亡风险相关.
科学领域:
- 关键护理医学 关键护理医学
- 内分泌学 在内分泌学.
- 临床研究 临床研究
背景情况:
- 血糖变化 (GV) 在重症患者中很常见.
- 早期识别GV标志物可以预测患者的结果.
- 了解GV的影响对于管理重症监护室 (ICU) 患者至关重要.
研究的目的:
- 为了研究早期血糖可变性参数与重症患者28天死亡率之间的关联.
- 为了确定特定的GV指标预测死亡率.
- 探索不同GV措施之间的关系.
主要方法:
- 一项前性观察性研究,涉及578名在土耳其五个重症监护室的重症患者.
- 在ICU入院后的前24小时内记录了血糖变化参数 (SD,MGL,MGD,CV).
- 利用多变量逻辑回归和斯皮尔曼的rho相关性进行分析.
主要成果:
- 患有较高CV,SD和MGD的患者显示28天死亡率增加.
- 变化系数 (CV) 被确定为死亡率的独立预测指标 (OR 1.023,p=0.017).
- 在CV和MGD之间发现了强烈的相关性 (r=0.871,p<0.001).
结论:
- 危急病患者的早期CV与28天死亡率独立相关.
- MGD与CV有很强的相关性,可以作为死亡风险评估的床边工具.
- 需要进一步的研究来确认MGD与死亡率的独立关联.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.2K
Hypoglycemia and Glucagon
152
Without prolonged fasting, healthy individuals maintain blood glucose levels above 3.5 mM due to a well-adapted neuroendocrine counterregulatory system that effectively prevents acute hypoglycemia, a potentially life-threatening condition. The primary clinical scenarios for hypoglycemia encompass diabetes treatment, inappropriate production of endogenous insulin or insulin-like substances by tumors, and the use of glucose-lowering agents in non-diabetic individuals. Notably, hypoglycemia in the...
152
Diabetes: Symptoms, Diagnosis, and Complications
506
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
506
Overview of Carbohydrate Metabolism
745
Carbohydrate metabolism is a fundamental biochemical process that ensures a constant supply of energy to living cells. The most important carbohydrate is glucose, which can be broken down via glycolysis to enter into the Krebs cycle and eventually lead to the production of ATP through oxidative phosphorylation.
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
745
SBAR II: Application of SBAR
4.3K
SBAR is an effective communication tool used by healthcare professionals to communicate patient information accurately. SBAR stands for Situation, Background, Assessment, and Recommendation. For a better understanding, an example is given below.
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
SBAR Report from a Nurse to a Health Care Provider
S: "Hello, Dr. Smith. This is Jane, RN, from the Med Surg unit. I am calling to tell you about Ms. White in Room 210, who is experiencing increased pain and redness at her incision site. Her recent...
4.3K

